Friend or Foe? A Deep Dive into This Ubiquitous Ingredient
May 20, 2025
Propylene glycol is one of those ingredients you’ve probably seen on a label without giving it much thought. It doesn’t sound fancy or botanical, and it’s not something influencers are raving about. But it’s in a surprising number of your products—serums, moisturizers, toners, even cleansers. Why? Because it works. Whether you’re building a minimalist routine or curating a 12-step ritual, understanding what this ingredient does (and doesn’t do) will help you make smarter skincare decisions.
Let’s break it down: what is propylene glycol, why is it used, what are its benefits, how do you use it, what are the risks, and are there different types that matter for your skin?
Propylene glycol is a synthetic, colorless, odorless liquid that’s derived from petroleum or natural gas. Chemically, it’s a diol—a molecule with two alcohol groups—making it water-soluble and highly versatile. In skincare, it's primarily used as a humectant, solvent, emollient, and preservative booster.
Despite the scary “chemical” reputation, it’s classified as safe by the FDA and the Cosmetic Ingredient Review (CIR) panel when used in appropriate concentrations. It's also used in food, pharmaceuticals, and even medical products like IV medications—so it's not just a cosmetic filler.
Propylene glycol doesn’t require any special timing or technique. It’s not an active ingredient in the way exfoliants or retinoids are, so there’s no risk of “overusing” it in the conventional sense. If a product contains it, here’s what to keep in mind:
Technically, yes—but most skincare products use the same basic form: 1,2-propanediol (the most common isomer of propylene glycol). That said, here’s how it’s often confused or interchanged:
Propylene glycol can cause mild irritation, especially in people with eczema, compromised skin barriers, or very sensitive skin. Allergic reactions are rare but possible. If you’ve ever reacted to a patch test product or prescription cream and didn’t know why—this might’ve been the culprit.
It’s gotten a bad rap mainly because it’s used in antifreeze—but that’s a different formulation and concentration. The skincare-grade version is highly purified and used in much lower concentrations.
If you’re following a “clean beauty” philosophy or trying to avoid petrochemical derivatives, propylene glycol might be one of the ingredients on your “no” list. Not because it’s unsafe, but because it doesn’t align with your values.
ProsConsHydrates skin by attracting waterCan cause irritation in very sensitive skinHelps other ingredients absorb betterOften misunderstood or stigmatizedEnhances product texture and stabilityDerived from petroleum (though now also available in bio-based versions)Works with most other ingredientsMay be avoided by clean beauty enthusiastsNon-comedogenic and generally safeRare risk of allergic contact dermatitis
Propylene glycol shows up all over the skincare aisle, including:
Outside of skincare, it's also used in deodorants, hair products, oral hygiene items, and even contact lens solutions.
Propylene glycol is like the reliable backup dancer of skincare—it’s not the star, but the show wouldn’t work without it. It makes other ingredients better, smoother, more effective. And while it might not be trendy, it's incredibly functional.
If your skin is sensitive, patch test first or look for products that use butylene glycol instead. But for most people, it’s a safe, effective, and even beneficial ingredient—one that deserves a little more appreciation for how quietly it does its job.
Bottom line? Don’t fear the glycol. Just know your skin, read your labels, and keep your routine balanced. And if you're chasing glow, hydration, or product performance—this humble ingredient is probably already helping more than you think.